GSK Augmentin 625mg Duo Tablet
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Augmentin 625 Duo contains amoxicillin trihydrate (500 mg) and potassium clavulanate (125 mg) in film-coated tablets, providing broad-spectrum antibiotic coverage for bacterial infections in dogs and cats. The clavulanate component prevents bacterial resistance, making this combination effective against infections that might not respond to amoxicillin alone. This medication is commonly used to treat skin infections, respiratory infections, urinary tract infections, and soft tissue infections in pets.
Dosage Guidelines
PRESCRIPTION REQUIRED - Always follow your veterinarian's specific instructions.
Dogs:
- Typical dose: 12.5-25 mg per kg body weight, twice daily
- One 625 mg tablet suitable for large dogs (25-50 kg)
- Administer with food to reduce gastrointestinal upset
- Treatment duration: 5-14 days depending on infection severity
Cats:
- Usually requires lower strength formulation
- Consult veterinarian for appropriate dosing
- May need tablet splitting or alternative form such as oral suspension
Tablets should preferably be administered whole. If splitting is necessary for dosing purposes, consult your veterinarian.
Key Contraindications
- Known hypersensitivity to penicillins or beta-lactam antibiotics
- History of liver dysfunction or cholestatic jaundice with amoxicillin-clavulanate
- Severe renal impairment without dose adjustment
- History of jaundice or hepatic dysfunction associated with this medication
- Infectious mononucleosis
Common Side Effects
- Gastrointestinal upset (vomiting, diarrhea)
- Loss of appetite
- Skin reactions, rash, or itching
- Lethargy
- Excessive drooling (especially in cats)
Stop medication and contact your veterinarian immediately if severe allergic reactions, persistent vomiting, bloody diarrhea, difficulty breathing, facial swelling, or yellowing of skin/gums occurs.
Drug Interactions
Augmentin 625 Duo may interact with several medications including:
- Probenecid (may increase amoxicillin blood levels)
- Allopurinol (increased risk of skin reactions)
- Anticoagulants like warfarin (may affect blood clotting)
- Other antibiotics (aminoglycosides, tetracyclines, chloramphenicol)
- Methotrexate (increased toxicity risk)
Inform your veterinarian of all medications and supplements your pet is taking.
Storage Requirements
- Store protected from moisture at temperature not exceeding 25°C (77°F)
- Keep in original blister packaging until use
- Store in a dry place away from direct sunlight and heat
- Keep out of reach of children and pets
- Do not use beyond expiration date
Important Safety Information
This is a prescription medication. Use only as directed by a licensed veterinarian.
Complete the full prescribed course even if symptoms improve to prevent antibiotic resistance. This medication works only against bacterial infections, not viral or parasitic conditions. Inform your veterinarian if your pet is taking other medications, as interactions may occur. Long-term or repeated use may require periodic liver and kidney function monitoring.
Note: This information is for educational purposes only and does not replace professional veterinary advice. Always consult your veterinarian before starting, stopping, or changing any medication. Your veterinarian will determine the appropriate dosage based on your pet's weight, condition severity, and overall health status.